Primary Neoplasm Risk Among Survivors of Cancer
In adolescents and young adult cancer survivors, the median age of subsequent diagnosis of breast, colorectal and lung cancers is lower than that of the general population.
- True
- False
Oncology
Prostate Cancer
A 65-year-old man who is otherwise well presents for a periodic health examination. He has a friend who recently was diagnosed with prostate cancer. He is requesting a prostate specific antigen (PSA) test. After discussion of the benefits and risks, you order the test. His PSA comes back markedly abnormal and remains elevated on repeat testing
Volume 41.4 - Question 33
Terminal Dyspnea in Cancer Patients
Which one of the following statements regarding terminal dyspnea in cancer patients is false?
- It is one of the most common and distressing symptoms in patients with advanced cancer.
- It can rapidly worsen as death approaches.
- Opioids lessen dyspnea regardless of clinician-predicted survival.
- Adverse events are not common in imminently dying patients.
Volume 41.4 - Question 26
Lung Cancer in Non-smokers
Which one of the following statements regarding lung cancer in non-smokers is false?
- It accounts for less than 10% of all lung cancers.
- Most are adenocarcinomas.
- Lung cancer in first degree relatives is a risk factor.
- Therapeutically targetable genomic variants are more common in tumors from nonsmoking individuals.
Volume 41.4 - Question 25
Neoplasm Related Eye Pain
Which one of the following statements regarding neoplasm-related eye pain is false?
- Systemic opioids have no role in managing pain.
- Over 50% of patients experience Phantom Eye Syndrome after undergoing enucleation.
- Preoperative pain is a risk factor for the development of Phantom Eye Syndrome after enucleation.
- The most common symptom of Phantom Eye Syndrome is phantom vision.
Volume 41.3 - Question 25
HPV Vaccination
One dose of either a bivalent or nonavalent human papillomavirus (HPV) vaccine provides protection against HPV16 or HPV18 infection and is not inferior to two doses.
- True
- False
Volume 41.3 - Question 1
Helicobacter pylori Eradication and Gastric Cancer
Eradication therapy in Helicobacter pylori-positive individuals reduces risk of gastric cancer.
- True
- False
Volume 41.2 - Question 34
Leptomeningeal Disease
Which one of the following statements about leptomeningeal disease is false?
- Autopsy studies suggest that it may often go undetected.
- Prognosis has historically been very poor with no treatment.
- Non-hematological cancers are associated with a better prognosis than hematologic cancers.
- Patients may present with signs of cauda equina syndrome.
Volume 41.1 - Question 37
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
A structured exercise program initiated soon after adjuvant chemotherapy for colon cancer results in significantly longer disease-free survival.
- True
- False
Volume 41.1 - Question 33
Elinzanetant for Vasomotor Symptoms in Breast Cancer
Elinzanetant treatment significantly lowers the frequency of vasomotor symptoms associated with endocrine therapy for breast cancer than placebo.
- True
- False
Volume 41.1 - Question 13
Significance of Coronary Calcium Seen on Lung Cancer Screening
Among people undergoing a low-dose chest CT for lung cancer screening, an incidental finding of extensive coronary artery calcium is an independent predictor of all-cause death and cardiovascular events.
- True
- False
Volume 40.4 - Question 28
Mammogram Screening Cost Effectiveness
Annual screening at ages 40 to 74 years was cost-effective and achieved the best breast cancer outcomes compared with biennial screening at ages 50 to 74 years.
- True
- False
Volume 40.3 - Question 38
Salpingectomy to Reduce Ovarian Cancer Risk
Which one of the following statements about salpingectomy for reducing the risk of ovarian cancer is false?
- High-grade serous ovarian cancer originates in the fallopian tube.
- All patients undergoing pelvic surgery who do not desire future pregnancy should be offered salpingectomy.
- Perioperative complications occur more frequently with salpingectomy compared to tubal ligation.
- Patients with BRCA1 should consider prophylactic salpingo-oophorectomy.
Volume 40.1 - Question 3
Progesterone and Intracranial Meningioma
The prolonged use of injectable medroxyprogesterone acetate is associated with an increase in the risk of intracranial meningioma.
- True
- False
Volume 39.6 - Question 18
Cell Phone Use and Brain Cancer
Long-term or heavy mobile phone use is associated with an increased risk of glioma.
- True
- False
Volume 39.6 - Question 6
Non-small Cell Lung Carcinoma
Which one of the following statements about targeted therapy for the treatment of non-small cell lung carcinoma is false?
- Tumour-related gene alterations cannot be identified from circulating tumour DNA in the patient’s blood.
- Targeted therapies do not cause notable immunosuppression.
- Most patients presenting with fever can be managed as per routine clinical practice.
- Targeted therapy can be administered orally as an outpatient.
Volume 39.5 - Question 40
Bladder Cancer
Which one of the following statements about bladder cancer is false?
- The most common presentation of bladder cancer is gross hematuria.
- Transurethral resection of bladder tumour is used purely for diagnosis.
- Non muscle invasive bladder cancer represents approximately 70% of organ-confined cancer.
- Patients with low risk disease who undergo resection are managed with cystoscopic surveillance.
Volume 36.4 - Question 36
Ovarian Cancer
General population screening for ovarian and tubal cancer has been shown to be effective at preventing ovarian and tubal cancer deaths.
- True
- False
Volume 37.1 - Question 23
Diagnosis of Cutaneous T Cell Lymphoma
Which one of the following statements about diagnosis of cutaneous T cell lymphoma is false?
- It often presents with nonspecific dermatological manifestations.
- Erythroderma (confluent lesions affecting 80% of body surface area) may be a feature.
- The median age at diagnosis with CTCL is 70.
- Patients may require multiple skin biopsies before a diagnosis is made.
Volume 37.4 - Question 14
Cutaneous T Cell Lymphoma
Which one of the following statements about Cutaneous T cell lymphoma is false?
- The second most common subtype is mycosis fungoides (MF).
- Both its variants predominantly involve the skin.
- Sézary syndrome (SS) is its leukemic variant.
- Both MF and SS can affect extracutaneous organs (such as viscera, lymph nodes and blood).
Volume 37.4 - Question 13
Barrett Esophagus Management
Which one of the following statements about the management of Barrett Esophagus is false?
- Patients with Barrett esophagus have approximately a 3% to 5% risk of developing esophageal adenocarcinoma in their lifetime.
- Screening for Barrett esophagus reduces death rates from esophageal adenocarcinoma.
- Surveillance endoscopy every 3-5 years is recommended for patients with nondysplastic disease.
- Resection of visible neoplastic Barrett esophagus lesions should be followed by ablation.
Volume 38.1 - Question 28
Liver Disease and Diet
In postmenopausal women, there is a statistically significant association between increased sugar-sweetened beverage intake and chronic liver disease mortality.
- True
- False