Oncology

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Neoplasm Related Eye Pain

Which one of the following statements regarding neoplasm-related eye pain is false?

  • Systemic opioids have no role in managing pain.
  • Over 50% of patients experience Phantom Eye Syndrome after undergoing enucleation.
  • Preoperative pain is a risk factor for the development of Phantom Eye Syndrome after enucleation.
  • The most common symptom of Phantom Eye Syndrome is phantom vision.
Volume 41.3 - Question 25

HPV Vaccination

One dose of either a bivalent or nonavalent human papillomavirus (HPV) vaccine provides protection against HPV16 or HPV18 infection and is not inferior to two doses.

  • True
  • False
Volume 41.3 - Question 1

Leptomeningeal Disease

Which one of the following statements about leptomeningeal disease is false?

  • Autopsy studies suggest that it may often go undetected.
  • Prognosis has historically been very poor with no treatment.
  • Non-hematological cancers are associated with a better prognosis than hematologic cancers.
  • Patients may present with signs of cauda equina syndrome.
Volume 41.1 - Question 37

Elinzanetant for Vasomotor Symptoms in Breast Cancer

Elinzanetant treatment significantly lowers the frequency of vasomotor symptoms associated with endocrine therapy for breast cancer than placebo.

  • True
  • False
Volume 41.1 - Question 13

Significance of Coronary Calcium Seen on Lung Cancer Screening

Among people undergoing a low-dose chest CT for lung cancer screening, an incidental finding of extensive coronary artery calcium is an independent predictor of all-cause death and cardiovascular events.

  • True
  • False
Volume 40.4 - Question 28

Mammogram Screening Cost Effectiveness

Annual screening at ages 40 to 74 years was cost-effective and achieved the best breast cancer outcomes compared with biennial screening at ages 50 to 74 years.

  • True
  • False
Volume 40.3 - Question 38

Salpingectomy to Reduce Ovarian Cancer Risk

Which one of the following statements about salpingectomy for reducing the risk of ovarian cancer is false?

  • High-grade serous ovarian cancer originates in the fallopian tube.
  • All patients undergoing pelvic surgery who do not desire future pregnancy should be offered salpingectomy.
  • Perioperative complications occur more frequently with salpingectomy compared to tubal ligation.
  • Patients with BRCA1 should consider prophylactic salpingo-oophorectomy.
Volume 40.1 - Question 3

Progesterone and Intracranial Meningioma

The prolonged use of injectable medroxyprogesterone acetate is associated with an increase in the risk of intracranial meningioma.

  • True
  • False
Volume 39.6 - Question 18

Cell Phone Use and Brain Cancer

Long-term or heavy mobile phone use is associated with an increased risk of glioma.

  • True
  • False
Volume 39.6 - Question 6

Non-small Cell Lung Carcinoma

Which one of the following statements about targeted therapy for the treatment of non-small cell lung carcinoma is false? 

  • Tumour-related gene alterations cannot be identified from circulating tumour DNA in the patient’s blood.   
  • Targeted therapies do not cause notable immunosuppression.   
  • Most patients presenting with fever can be managed as per routine clinical practice.   
  • Targeted therapy can be administered orally as an outpatient. 
Volume 39.5 - Question 40

Bladder Cancer

Which one of the following statements about bladder cancer is false? 

  • The most common presentation of bladder cancer is gross hematuria.   
  • Transurethral resection of bladder tumour is used purely for diagnosis.   
  • Non muscle invasive bladder cancer represents approximately 70% of organ-confined cancer.   
  • Patients with low risk disease who undergo resection are managed with cystoscopic surveillance. 
Volume 36.4 - Question 36

Ovarian Cancer

General population screening for ovarian and tubal cancer has been shown to be effective at preventing ovarian and tubal cancer deaths.

  • True
  • False
Volume 37.1 - Question 23

HIV and Anal Carcinoma

Patients with HIV who have a history of anogenital warts have an increased risk of developing anal carcinoma.  

  • True
  • False
Volume 36.3 - Question 18

Endometrial Cancer

Which one of the following statements about endometrial cancer is false? 

  • Obesity is a risk factor.   
  • Reduced risk from prolonged oral contraceptive use does not persist after discontinuation.   
  • For early cancers, the use of a progestin-containing intrauterine device is an alternative to hysterectomy.   
  • Lifetime risk is at least 40% in women with Lynch syndrome. 
Volume 36.3 - Question 7

Diagnosis of Cutaneous T Cell Lymphoma

Which one of the following statements about diagnosis of cutaneous T cell lymphoma is false?

  • It often presents with nonspecific dermatological manifestations.
  • Erythroderma (confluent lesions affecting 80% of body surface area) may be a feature.
  • The median age at diagnosis with CTCL is 70.
  • Patients may require multiple skin biopsies before a diagnosis is made.
Volume 37.4 - Question 14

Cutaneous T Cell Lymphoma

Which one of the following statements about Cutaneous T cell lymphoma is false?

  • The second most common subtype is mycosis fungoides (MF).
  • Both its variants predominantly involve the skin.
  • Sézary syndrome (SS) is its leukemic variant.
  • Both MF and SS can affect extracutaneous organs (such as viscera, lymph nodes and blood).
Volume 37.4 - Question 13

Barrett Esophagus Management

Which one of the following statements about the management of Barrett Esophagus is false? 

  •  Patients with Barrett esophagus have approximately a 3% to 5% risk of developing esophageal adenocarcinoma in their lifetime. 
  • Screening for Barrett esophagus reduces death rates from esophageal adenocarcinoma. 
  • Surveillance endoscopy every 3-5 years is recommended for patients with nondysplastic disease. 
  • Resection of visible neoplastic Barrett esophagus lesions should be followed by ablation. 
Volume 38.1 - Question 28

Liver Disease and Diet

In postmenopausal women, there is a statistically significant association between increased sugar-sweetened beverage intake and chronic liver disease mortality. 

  • True
  • False
Volume 39.1 - Question 35

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