Helicobacter pylori Eradication and Gastric Cancer
Eradication therapy in Helicobacter pylori-positive individuals reduces risk of gastric cancer.
- True
- False
Oncology
Leptomeningeal Disease
Which one of the following statements about leptomeningeal disease is false?
- Autopsy studies suggest that it may often go undetected.
- Prognosis has historically been very poor with no treatment.
- Non-hematological cancers are associated with a better prognosis than hematologic cancers.
- Patients may present with signs of cauda equina syndrome.
Volume 41.1 - Question 37
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
A structured exercise program initiated soon after adjuvant chemotherapy for colon cancer results in significantly longer disease-free survival.
- True
- False
Volume 41.1 - Question 33
Elinzanetant for Vasomotor Symptoms in Breast Cancer
Elinzanetant treatment significantly lowers the frequency of vasomotor symptoms associated with endocrine therapy for breast cancer than placebo.
- True
- False
Volume 41.1 - Question 13
Significance of Coronary Calcium Seen on Lung Cancer Screening
Among people undergoing a low-dose chest CT for lung cancer screening, an incidental finding of extensive coronary artery calcium is an independent predictor of all-cause death and cardiovascular events.
- True
- False
Volume 40.4 - Question 28
Mammogram Screening Cost Effectiveness
Annual screening at ages 40 to 74 years was cost-effective and achieved the best breast cancer outcomes compared with biennial screening at ages 50 to 74 years.
- True
- False
Volume 40.3 - Question 38
Salpingectomy to Reduce Ovarian Cancer Risk
Which one of the following statements about salpingectomy for reducing the risk of ovarian cancer is false?
- High-grade serous ovarian cancer originates in the fallopian tube.
- All patients undergoing pelvic surgery who do not desire future pregnancy should be offered salpingectomy.
- Perioperative complications occur more frequently with salpingectomy compared to tubal ligation.
- Patients with BRCA1 should consider prophylactic salpingo-oophorectomy.
Volume 40.1 - Question 3
Progesterone and Intracranial Meningioma
The prolonged use of injectable medroxyprogesterone acetate is associated with an increase in the risk of intracranial meningioma.
- True
- False
Volume 39.6 - Question 18
Cell Phone Use and Brain Cancer
Long-term or heavy mobile phone use is associated with an increased risk of glioma.
- True
- False
Volume 39.6 - Question 6
Non-small Cell Lung Carcinoma
Which one of the following statements about targeted therapy for the treatment of non-small cell lung carcinoma is false?
- Tumour-related gene alterations cannot be identified from circulating tumour DNA in the patient’s blood.
- Targeted therapies do not cause notable immunosuppression.
- Most patients presenting with fever can be managed as per routine clinical practice.
- Targeted therapy can be administered orally as an outpatient.
Volume 39.5 - Question 40
Bladder Cancer
Which one of the following statements about bladder cancer is false?
- The most common presentation of bladder cancer is gross hematuria.
- Transurethral resection of bladder tumour is used purely for diagnosis.
- Non muscle invasive bladder cancer represents approximately 70% of organ-confined cancer.
- Patients with low risk disease who undergo resection are managed with cystoscopic surveillance.
Volume 36.4 - Question 36
Ovarian Cancer
General population screening for ovarian and tubal cancer has been shown to be effective at preventing ovarian and tubal cancer deaths.
- True
- False
Volume 37.1 - Question 23
HIV and Anal Carcinoma
Patients with HIV who have a history of anogenital warts have an increased risk of developing anal carcinoma.
- True
- False
Volume 36.3 - Question 18
Endometrial Cancer
Which one of the following statements about endometrial cancer is false?
- Obesity is a risk factor.
- Reduced risk from prolonged oral contraceptive use does not persist after discontinuation.
- For early cancers, the use of a progestin-containing intrauterine device is an alternative to hysterectomy.
- Lifetime risk is at least 40% in women with Lynch syndrome.
Volume 36.3 - Question 7
Post-menopausal Hormone Therapy and Breast Cancer
The use of conjugated equine estrogen (CEE) for the treatment of menopause in women with prior hysterectomy is associated with a statistically significantly lower incidence of breast cancer.
- True
- False
Volume 36.2 - Question 24
Diagnosis of Cutaneous T Cell Lymphoma
Which one of the following statements about diagnosis of cutaneous T cell lymphoma is false?
- It often presents with nonspecific dermatological manifestations.
- Erythroderma (confluent lesions affecting 80% of body surface area) may be a feature.
- The median age at diagnosis with CTCL is 70.
- Patients may require multiple skin biopsies before a diagnosis is made.
Volume 37.4 - Question 14
Cutaneous T Cell Lymphoma
Which one of the following statements about Cutaneous T cell lymphoma is false?
- The second most common subtype is mycosis fungoides (MF).
- Both its variants predominantly involve the skin.
- Sézary syndrome (SS) is its leukemic variant.
- Both MF and SS can affect extracutaneous organs (such as viscera, lymph nodes and blood).
Volume 37.4 - Question 13
Barrett Esophagus Management
Which one of the following statements about the management of Barrett Esophagus is false?
- Patients with Barrett esophagus have approximately a 3% to 5% risk of developing esophageal adenocarcinoma in their lifetime.
- Screening for Barrett esophagus reduces death rates from esophageal adenocarcinoma.
- Surveillance endoscopy every 3-5 years is recommended for patients with nondysplastic disease.
- Resection of visible neoplastic Barrett esophagus lesions should be followed by ablation.
Volume 38.1 - Question 28
Liver Disease and Diet
In postmenopausal women, there is a statistically significant association between increased sugar-sweetened beverage intake and chronic liver disease mortality.
- True
- False