A liberal transfusion threshold, targeting a hemoglobin of 9g/dL compared to a restrictive strategy targeting a hemoglobin of 7g/dL, was associated with a lower risk of unfavorable neurological outcome at 180 days in patients with acute brain injury.
Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation (bilevel positive airway pressure) results in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask.
In patients with acute brain injury, a single (2g) ceftriaxone dose decreased the risk of early ventilator-associated pneumonia.
Among patients with suspected sepsis treated with vancomycin and no clear indication for anti-anaerobic coverage, administration of piperacillin-tazobactam is associated with higher mortality compared with cefepime.
The likelihood of favorable functional status for patients with in-hospital cardiac arrest receiving CPR for 32 minutes or longer is less than 1%.
Which one of the following statements about vitamin K prophylaxis in newborns is false?
Comparing early vs. late initiation of norepinephrine in patients with septic shock, each of the following is decreased except:
Among critically ill patients requiring fluid challenges, use of a balanced solution compared with 0.9% saline solution significantly reduces 90-day mortality.
Among critically ill adults undergoing tracheal intubation, administration of an intravenous fluid bolus compared with no fluid bolus significantly decreased the incidence of cardiovascular collapse.
Among patients in the ICU with delirium, treatment with haloperidol will lead to a significantly fewer days alive and out of the hospital at 90 days than placebo.
In non-intubated adults with hypoxemic respiratory failure due to covid-19, awake prone positioning compared with usual care results in which one of the following significantly improved outcomes?